Unusual Localised Skin Reaction due to Ondansetron: Case Series


  • Sumandeep Vidyapeeth Deemed University, Department of Pharmacology, Smt B. K. Shah Medical Institute and Research Centre, Gujarat, 391760, India
  • GMERS Medical College, Department of Paediatric, Vadodara, Gujarat, 390021, India
  • Nootan Medical College and Research Centre, Department of Pharmacology, Visnagar, Gujarat, 384315, India
  • Sumandeep Vidyapeeth Deemed University, Department of Physiology, Smt B.K Shah Medical Institute and Research Centre, Vadodara, Gujarat, 391760, India


Ondansetron is an antiemetic drug that belongs to 5-hydroxytryptamine (5-HT3) receptor antagonists group. It has been widely used to treat nausea and vomiting due to chemotherapy, post surgery or due to any other gastrointestinal problem with 5-HT3 receptors involvement. The typical adverse drug reactions of Ondansetron include headache, dizziness, constipation or diarrhoea. Here, we have observed the skin reaction around the site of injection following Ondansetron administration. Recognition of this hypersensitivity reaction may allow better preparedness of clinicians to manage this condition.


Ondansetron, 5-HT3, Skin Reaction

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